Mesna is utilized therapeutically to reduce a incidence of haemorrhagic cystitis and haematuria when a patient receives ifosfamide or even cyclophosphamide for cancer chemotherapy. These deuce antitumor agencies, inside vivo, can be converted to urotoxic metabolites like acrolein. Mesna helps to neutralise these metabolites by binding across its sulfhydryl-moieties, and besides increases urinary excretion of cysteine.

fr:Mesna